Table of Contents
Non-Steroidal Anti-Inflammatories (NSAIDs)
These drugs belong to an old class of medications which have been around for several decades.
These drugs are used to treat a wide variety of conditions ...allergic reactions, auto-immune disorders, rejection episodes in patients with transplants, pneumonia, asthma, Stevens-Johnson Syndrome, joint inflammation, pain, swelling, etc.
The basic pharmaceutical reasons to use NSAIDs are :
NSAIDs Are Anti-Inflammatory
The anti-inflammatory properties of the NSAIDs insure that the release of the prostaglandins, histamines, thromboxanes and leukotrienes is inhibited in the area of tissue injury.
Functions Of Prostaglandins
Directly Cause Pain
Functions Of Histamines
causes sneezing, watery eyes, itching
Functions Of Thromboxanes
Functions Of Leukotrienes
act as powerful chemotactic signals for :
NSAIDs Are Analgesic Agents
NSAIDs Are Antipyretic
NSAIDs Are Anti-Coagulants
NSAIDs... A Host Of Drugs
The Salicylates
Salicylate-Like NSAIDs
Piroxicam - Feldene
Fenoprofen Calcium - Nalfon
Medical Uses For NSAIDs
Used as an anti-inflammatory in patients with bursitis, tendonitis, traumatic soft tissue damage, auto-immune defense disorders, etc.
Gouty Arthritis
Special Uses For NSAIDs
Aspirin
Ibuprofen
Adverse Side Effects Of The NSAIDs
GI Tract :
nausea
Kidneys :
Eyes :
Hematopoietic Effects :
leukopenia (low WBC count)
Signs Of NSAID Overdose
visual disturbances
bronchoconstriction
Special Problems Associated With Salicylate Usage In Children
Reyes Syndrome - Signs/Symptoms
intense combativeness
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Author: Microsoft Corporation
Email: David.Arnall@NAU.EDU , DAArnall@AOL.COM
Home Page: http://jan.ucc.nau.edu/~daa/pt675/
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